The glucose metabolism disorder and dyslipidemia among girls with different phenotype polycystic ovary syndrome

Background: This study aimed to determine the prevalence of glucose metabolism disorder and dyslipidemia in 14–18‑year‑old girls with different phenotype polycystic ovary syndrome (PCOS). Materials and Methods: This descriptive, cross‑sectional study was conducted on 3200 high‑school adolescents aged 14–18 years in Shiraz in 2010.  Selected parameters of metabolic syndrome (fasting blood glucose, glucose tolerance test [GTT], insulin level, triglyceride (TG), cholesterol, and high‑density lipoprotein [HDL]), based on adult treatment panel Ш definition criteria, were compared between the “PCOS” and control groups. Results: Results were compared at four main phenotypes. The level of serum TG was increased in the Phenotype B (P = 0.03) and Phenotype D (P = 0.01), compared to the control group. Cholesterol and low‑density lipoprotein levels (P < 0.05) and GTT (P > 0.05) were increased, and HDL was decreased (was below 50) in all the four phenotypes and the control group (P > 0.05). Conclusion: The risk of metabolic alterations of glucose metabolism disorder and dyslipidemia in PCOS adolescents was more than non‑PCOS counterparts.