Molecular Identification of MefE and AmpC Resistance Genes in ATCC Bacteria

Enterococci are gram-positive bacteria and the source of recurrent nosocomial infections with high levels of antibiotic resistance (1), of which we can name resistance to cephalosporins, aminoglycosides, monobactams, penicillinase resistance penicillins, and most importantly, vancomycin (2). Between 85% to 90% of the enterococci infections are caused by Enterococcus faecium (2), and macrolide-lincosamide-streptogramin is an antibiotic, which can be useful for treating enterococcal infections (1). M phenotype refers to a resistance mechanism to macrolides (such as erythromycin) and includes activedrug efflux pumps that are encoded by mef genes (3,4). For the first time, bacterial antibiotic efflux was reported in 1970 (3). The presence of mef genes have been reported in previous studies (6). In the current study, we reported mefE gene in E. faecium ATCC (American Type Culture Collection) 51559. Acinetobacter baumannii is a gramnegative bacterium that has turned into a great concern in the health care centers especially in intensive care units (4).