Author/Authors :
Valiollahi Bijan Bone and Joint Reconstruction Research Center - Shafa Orthopedic Hospital - Iran University of Medical Sciences - Tehran, Iran , Salehpour Mostafa Bone and Joint Reconstruction Research Center - Shafa Orthopedic Hospital - Iran University of Medical Sciences - Tehran, Iran , Bashari Hamidreza Bone and Joint Reconstruction Research Center - Shafa Orthopedic Hospital - Iran University of Medical Sciences - Tehran, Iran , Majdi Shoeib Bone and Joint Reconstruction Research Center - Shafa Orthopedic Hospital - Iran University of Medical Sciences - Tehran, Iran , Mohammadpour Mehdi Bone and Joint Reconstruction Research Center - Shafa Orthopedic Hospital - Iran University of Medical Sciences - Tehran, Iran
Abstract :
Bisphosphonates, more particularly alendronate, are a popular category of drugs in the treatment
of postmenopausal and corticosteroid-induced osteoporosis. The present study contends that the
long-term consumption of bisphosphonates causes not only subtrochanteric and femoral shaft
fractures but also pathological fractures at other musculoskeletal sites. This report presents a
rare case of alendronate-induced pathological metatarsal fracture in a 59-year-old female with a
history of cuboid fracture following a twisting with abnormal Bone Mineral Density (BMD) (T
score: −3.5; lumbar spine and −2.6; proximal femur).