Title of article :
Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study
Author/Authors :
Osouli Alamdari, Mahak Department of Medical Physics and Biomedical Engineering - Tehran University of Medical Sciences , Ghafarian, Pardis Chronic Respiratory Diseases Research Center - National Research Institute of Tuberculosis and Lung Diseases - Shahid Beheshti University of Medical Sciences , Geramifar, Parham Research Center for Nuclear Medicine - Shariati Hospital - Tehran University of Medical Sciences , Ay, Mohammad Reza Department of Medical Physics and Biomedical Engineering - Tehran University of Medical Sciences
Abstract :
Purpose: Positron Emission Tomography (PET) imaging is a nuclear medicine imaging technique based on the recording of two photons as coincidence created by positron annihilation.
Materials and Methods: PET coincidence events include true and unwanted coincidences (random, scattered, multiple coincidences). We modeled the Discovery 690 (D-690) PET scanner using the GATE simulation tool and estimated the effect of the diameter of the scattering medium out of the Axial Field of View (AFOV) on the random coincidence rates.
Results: The validation results indicated that the average difference between simulated and measured data for sensitivity and scatter fraction tests are 5% and 3%, respectively. Moreover, the results revealed that the increasing diameter of the scattering medium out of the AFOV has a direct effect on the random coincidence rates within the Field of View (FOV).
Conclusion: The study concluded that the presence of a scattering medium near the FOV increases the rate of random coincidences.
Keywords :
Positron Emission Tomography , Random Coincidences , Noise Equivalent Count Rate , Monte Carlo , Scatter Medium
Journal title :
Frontiers in Biomedical Technologies
