Title of article :
Green and catalyst-free synthesis of thiazole-imin derivatives
Author/Authors :
Rostami-Charati, Faramarz Department of Chemistry - Gonbad Kavous University, Gonbad , Karami, Hossein Department of Chemistry - Islamic Azad University, Qaemshahr
Abstract :
Functionalized thiazoles are generated from the reaction of dimethyl acetylenedicarboxylate, benzoylisothiocyanates
and primary amines and trialkyl phosphite in water. Particularly valuable features of this method include high yields of
products, broad substrate scope, short reaction time and straightforward procedure.
Keywords :
Thiazoles , Phosphonate , Primary amines , Phosphites , Activated acetylenic compound , Benzoylisothiocyanates
Journal title :
Iranian Journal of Organic Chemistry