Author/Authors :
Devrim, Tuba Departments of Pathology - Faculty of Medicine - Kýrýkkale University - 71450 - Kýrýkkale, Turkey , Ataç, Fatih Departments of Urology - Faculty of Medicine - Kýrýkkale University - 71450 - Kýrýkkale, Turkey , Altunkaya, Canan Departments of Pathology - Faculty of Medicine - Kýrýkkale University - 71450 - Kýrýkkale, Turkey , Özbek, Ayºe Departments of Pathology - Faculty of Medicine - Kýrýkkale University - 71450 - Kýrýkkale, Turkey , Özdemir, Gülhan Departments of Pathology - Faculty of Medicine - Kýrýkkale University - 71450 - Kýrýkkale, Turkey , Eryol, Merve Departments of Pathology - Faculty of Medicine - Kýrýkkale University - 71450 - Kýrýkkale, Turkey
Abstract :
Plasmacytoid urothelial carcinoma is a rare and aggressive form of urothelial carcinoma characterized with delayed
presentation and poor prognosis. Very few cases of this carcinoma have been reported in the literature. Here,
we report and discuss two cases of bladder plasmacytoid urothelial carcinoma of a 57-year-old male presented
with renal colic, and a 33-year-old female presented with macroscopic hematuria. Pathologic examinations of the
transurethral biopsies revealed urothelial carcinoma with plasmacytoid appearance. Subsequently, immunohistochemical
evaluation showed positive expression of epithelial markers and CD138. Additionally, losing of the
membranous expression of E-cadherin verified the diagnosis of plasmacytoid urothelial carcinoma.
Keywords :
plasmacytoid , urothelial carcinoma , CD138 , E-cadherin
