Author/Authors :
Shakeri, Farzaneh North Khorasan University of Medical Sciences, Bojnurd , Hosseini, Mahmoud Mashhad University of Medical Sciences, Mashhad , Ghorbani, Ahmad Mashhad University of Medical Sciences, Mashhad
Abstract :
Introduction: Various pharmacological effects of Ocimum basilicum (O. basilicum)
have been investigated including: antioxidant, antibacterial, anti-ulcerogenic, cardiac
stimulant, hypoglycemic, hypolipidemic, hepatoprotective, anti-inflammatory,
anticancer and immunomodulatory properties. It has also the beneficial effects in
nervous system disorders, reproductive disorders and respiratory diseases. In this
article the neuropharmacological effects of O. basilicum and its constituents is
reviewed.
Methods: The data was gathered by searching: PubMed, Science Direct, Scopus
and Google Scholar using the following key words: Basil, O. basilicum,
neuropharmacological, neurotoxicity, neurodegeneration, memory, learning, epilepsy,
pain, anticonvulsant, antianxiety, anxiety, depression and anti-depressant.
Results: This review indicates that O. basilicum and its constituents have various
properties including anti-depression, anti-anxiety, anti-analgesic, anti-nociceptive and
memory enhancer which are probably due to its antioxidant property of O. basilicum.
Conclusion: It seems that O. basilicum and its constituents could be of therapeutic
values in nervous system diseases.
Keywords :
O. basilicum , Seizure , Depression , Anxiolytic , Analgesic
