Author/Authors :
Allameh, Farshad Department of Gastroenterology - Tehran University of Medical Sciences , Shateri Amiri, Bahareh Department of Internal Medicine - Tehran University of Medical Sciences , Zarei Jalalabadi, Narjes Department of Internal Medicine - Tehran University of Medical Sciences
Abstract :
In December 2019, a novel coronavirus (COVID19) was detected in Wuhan Hubei province, China.
The virus has caused a global concern because of
its high potential for transmission, high morbidity
and mortality. COVID-19 spreads so rapidly across
an increasing number of countries worldwide that
it has been found in more than 200 countries so
far. The World Health Organization (WHO) has
declared COVID-19 a pandemic and public health
threat (1-3)
. In general, COVID-19 is an infectious
disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). A case
fatality rate of approximately 2.3% has been
reported for COVID-19. New fever, cough,
lymphopenia and bilateral lung infiltrations are
characteristic but not diagnostic for COVID-19.
Sore throat, dyspnea, myalgia, diarrhea, and
abdominal pain are other presentations of COVID19. We should also be attentive to the probability
of atypical presentations in patients who are
immunocompromised. While the majority of cases
result in mild respiratory tract symptoms like
acute bronchitis, severe cases might end in severe
pneumonia, acute respiratory distress syndrome
(ARDS), septic shock and death due to multiorgan
damage, so early recognition of patients with
suspected COVID-19 infection is crucial. The
burden of the virus is not limited to physical
damage, but it also has a significant impact on the
mental health of the public. It can lead to
generalized anxiety disorders and depression
during COVID-19 pandemic (1, 4, 5)
. Now many
countries are in a state of crisis worldwide.
Whenever the living environment changes, people feel unsafe. People's fear of COVID-19 makes them
refrain from going to medical centers, which
significantly impacts their access to medical care
while they require acute treatment. COVID-19
outbreak in countries has pulled essential medical
resources away from regular procedures. This has
caused complications for patients who need
treatment for other medical conditions that
require timely and appropriate care. Cancer
patients especially still require attention in curative or palliative settings, and women will still
be delivering their infants. How can we care for
these patients without exposing them to COVID19? Now many patients try to avoid going to the
emergency room which is filled with patients
suspected of COVID-19. For example, in our
center, Imam Khomeini Hospital Complex, which
admitted an average of 50 patients to emergency
wards on a daily basis, this number has decreased
to 3 patients daily. Furthermore, when many of
these patients finally arrive, their clinical
conditions are more severe (2, 5). For example, a
57-year-old man came to our emergency ward
with a history of abdominal pain and vomiting
from 10 days ago. He was ill and toxic, and had
high grade fever, tachycardia and hypotension,
oliguria from 12 hours before coming to the
hospital. His laboratory tests showed elevated
levels of amylase, lipase and creatinine and
leukocytosis. He was admitted with impression of
necrotizing pancreatitis. We visited more than 20
patients with chronic liver failure with the
impression of decompensated cirrhosis who came
to us with sever ascites, hyperkalemia,
hepatorenal syndrome or encephalopathy. We
encountered with patients with chronic kidney
disease who did not oblige to their dialysis
program regularly and came to us with uremic
status. There were many diabetic patients that
came to clinics with poorly controlled diabetes
(Hemoglobin A1C>8%) and also diabetic
ketoacidosis which postponed their routine
diabetes care. A 22-year-old woman with a history
of cholecystectomy (4 years ago) came to us with abdominal pain from 15 days ago, fever and
jaundice. Her blood pressure was 60/40 mmHg,
her pulse rate was 140/min, and she had
tachypnea and high temperature upon admission
to the emergency room. On sonography,
radiologists reported dilated common bile duct,
and the patient was admitted with impression of
severe cholangitis and septic shock. Indeed, they
all postponed receiving care. There will still be
patients in outpatient, elective and non-elective settings requiring care. Furthermore, some
patients need diagnostic services (e.g. a young
woman with a breast mass) or they may also need
ongoing therapy for a chronic medical condition
such as solid organ transplants, malignancies,
rheumatologic disease. Non-elective patients such
as those with heart attack, stroke, pancreatitis,
gastrointestinal bleeding, fulminant hepatitis,
cholangitis, acute leukemia, multiple trauma and
other infections requiring medical care should be
managed to avoid delays in treatment. There are
some diagnostic procedures such as angiography
gasteroesophagoscoy and biopsies that the
patients may need in the course of treatment.
Therefore, we need to meet the medical needs of
patients with chronic diseases such as cancer,
chronic kidney disease and those who need longterm maintenance treatment. The day to day
medical service of some groups of people, such as
pregnant women and older adults are also very
important.