Title of article :
Propargylic ureas as powerful and versatile building blocks in the synthesis of various key medicinal heterocyclic compounds
Author/Authors :
Farshbaf ، Sepideh Department of Chemistry - Center for Photochemical Sciences - Bowling Green State University , Sreerama ، Lakshmaiah Department of Chemistry and Earth Sciences - College of Arts and Science - Qatar University , Khodayari ، Torkan Department of Chemistry - Islamic Azad University, Tabriz Branch , Vessally ، Esmail Department of Chemistry - Payame Noor University
Abstract :
This review article is an attempt to highlight the most important contributions toward the synthesis of various nitrogen-containing heterocyclic compounds from corresponding propargylic ureas through regio- and chemoselective 5-exo-dig and 6-endo-dig modes of N- and O-cyclization reactions. The review is divided into three major sections. In the first section we only focus on 5-exo-dig N-cyclization fashion. In the second section 5-exo-dig O-cyclization is described. The third section is devoted to 6-endo-dig N- and O-cyclizations.
Keywords :
propargylic ureas , 5 , exo , dig cyclization , 6 , endo , dig cyclization , Heterocyclic compounds
Journal title :
Chemical Review and Letters
