Author/Authors :
Pergolizzi Jr, Joseph V. NEMA Research - Inc. - Naples - Florida, USA , Magnusson, Peter Centre for Research and Development - Uppsala University/Region Gävleborg - Gävle, Sweden - Cardiology Research Unit - Department of Medicine - Solna - Karolinska Institutet - Stockholm, Sweden , LeQuang, Jo Ann NEMA Research - Inc. - Naples - Florida, USA , Breve, Frank NEMA Research - Inc. - Naples - Florida, USA , Paladini, Antonella Department MESVA - University of L’Aquila - 67100 L’Aquila, Italy , Rekatsina, Martina Anaesthetic Fellow - Moorfields Eye Hospital - London, UK , Yeam, Cheng Teng Duke-NUS Medical School - 8 College Road - Singapore 169857, Singapore , Imani, Farnad Pain Research Center - Iran University of Medical Sciences, Tehran , Saltelli, Giorgia Sant’Andrea Hospital - La Sapienza University - COVID Section - Roma, Italy , Taylor Jr, Robert NEMA Research - Inc. - Naples - Florida, USA , Wollmuth, Charles NEMA Research - Inc. - Naples - Florida, USA , Varrassi, Giustino Paolo Procacci Foundation - Via Tacito 7 - 00193 - Rome, Italy
Abstract :
The emergence of a novel coronavirus and coronavirus disease 2019 (COVID-19) represents a challenge to global healthcare. In the
past 20 years, this is the third coronavirus that jumped the species barrier and infected humans. It is highly contagious but associated
with low pathogenicity. First identified inWuhan, China, a city of over 11 million, the disease has since spread to every continent
except Antarctica. About 15% to 20% of all casesmaybe called severe, and it is believedmanycases are asymptomatic. The average age
of a person with COVID has been reported as 49 years. Worse outcomes are associated with geriatric populations and those with underlying
diseases such as cardiovascular, respiratory disorders, and/or diabetes. The coronavirus, like other coronaviruses, is highly
contagious and has a latency period of about 14 days. Most patients present with fever and a dry cough, but fever may be absent.
Differential diagnosis can be challenging since influenza may present with similar symptoms. Chest radiography or computed tomography
may be used to find evidence of secondary pneumonia. Nosocomial infection is of concern, and it has been reported that
3.8% of all cases with COVID-19 in that country involve healthcare workers in China. Most patients have mild disease, and supportive
care suffices. A variety of repurposed and investigational drugs are being evaluated. There are currently no antiviral therapies or
vaccines, even if many therapies are proposed. Hand hygiene, social distancing, and scientifically sound information are the best
strategies at the moment to combat this epidemic.
Keywords :
Infection , MERS , Corticosteroids , Anti-inflammatory , NSAIDs , COVID-19 , Coronavirus , SARS