Author/Authors :
Yousefkhani, Leila Skin Research Center - Guilan University of Medical Sciences - Razi Hospital, Rasht , Eftekhari, Hojat Skin Research Center - Guilan University of Medical Sciences - Razi Hospital, Rasht , Rafiei, Rana Skin Research Center - Guilan University of Medical Sciences - Razi Hospital, Rasht , Nikkhah, Nahid Department of Pathology - NYU Winthrop Hospital - New York - United States , Rafiee, Behnam Skin and Stem Cell Research Center - Tehran University of Medical Sciences
Abstract :
Introduction: Reed syndrome is a rare autosomal dominant disorder with a genetic defect in the fumarate hydratase. Patients
with Reed syndrome have multiple cutaneous leiomyomas, uterine leiomyomas or leiomyosarcomas with increased risk of renal
carcinoma.
Case Presentation: The current study presented a 57-year-old female with multiple cutaneous and uterine leiomyomatosis with a
positive family history. She and her family had no evidence of renal carcinoma.
Conclusions: Multiple skin leiomyomas could be considered as a cutaneous marker for uterine leiomyomatosis and possible renal
cell carcinoma in the familial presentations.
