Title of article
Reed Syndrome; Multiple Cutaneous and Uterine Leiomyomatosis
Author/Authors
Yousefkhani, Leila Skin Research Center - Guilan University of Medical Sciences - Razi Hospital, Rasht , Eftekhari, Hojat Skin Research Center - Guilan University of Medical Sciences - Razi Hospital, Rasht , Rafiei, Rana Skin Research Center - Guilan University of Medical Sciences - Razi Hospital, Rasht , Nikkhah, Nahid Department of Pathology - NYU Winthrop Hospital - New York - United States , Rafiee, Behnam Skin and Stem Cell Research Center - Tehran University of Medical Sciences
Pages
4
From page
1
To page
4
Abstract
Introduction: Reed syndrome is a rare autosomal dominant disorder with a genetic defect in the fumarate hydratase. Patients
with Reed syndrome have multiple cutaneous leiomyomas, uterine leiomyomas or leiomyosarcomas with increased risk of renal
carcinoma.
Case Presentation: The current study presented a 57-year-old female with multiple cutaneous and uterine leiomyomatosis with a
positive family history. She and her family had no evidence of renal carcinoma.
Conclusions: Multiple skin leiomyomas could be considered as a cutaneous marker for uterine leiomyomatosis and possible renal
cell carcinoma in the familial presentations.
Keywords
Reed Syndrome , Cutaneous Leiomyomatosis , Uterine Leiomyomatosis
Journal title
Journal of Skin and Stem Cell
Serial Year
2018
Record number
2504458
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