Author/Authors :
Ebrahimpour, Adel Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Chehrassan, Mohammadreza Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Sadighi, Mehrdad Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Azizmohammad Looha, Mehdi Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Karimi, Amin Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Akbari, Atieh Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Raeisi, Alireza Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Akbari, Mohammad Esmaeil Research performed at Cancer Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Background: The effect of race and ethnicity on some kind of malignant bone tumors including Ewing sarcoma
has been proven in different studies. In order to evaluate the latter, national cancer registries may help to increase
understanding about potential cancer causes, prevention and control strategies, and apply these findings to control
health problems among populations with similar characteristics.
Methods: A national population-based cancer registry study based on all patients affected by Ewing Sarcoma was
registered in the Iran National Cancer Registry (INCR) between 2008 and 2015 was designed. Demographic data of
microscopically confirmed cases of bone Ewing sarcoma were registered. Patients with Ewing sarcoma were divided
in groups to describe the primary site of the tumor (including axial or appendicular bones) and analyzed. In order to
analyze the survival rate, randomized selection of the patient through the INCR data-base was performed.
Results: A total of 678 cases of malignant Ewing sarcoma of the bone were identified through the INCR. The mean
age of Ewing sarcoma in Iran was 21.53 years. Nearly half of patients were observed at the age group of 15-24. The
total crude incidence rate of Ewing sarcoma was 1.29 in 1 million. The mean 5 year survival rate was 47%. The Mean
survival rate for study population was 5.53.
Conclusion: The crude incidence rate of Ewing sarcoma in Iran is relatively lower with respect to other registries. The
majority of patients are in 15-25 years group and shows affection by Ewing sarcoma in an older age. Socioeconomic
factors had direct influence on survival rate.
