Title of article :
Cutaneous Plasmacytoma: A Case Report
Author/Authors :
Asavisanu, Kalaprapa Department of Dermatology - Walsall Manor Hospital - Walsall - England , Kasparis, Christos Department of Dermatology - Walsall Manor Hospital - Walsall - England , Hock, Ye Lin Department of Histopathology - Walsall Manor Hospital - Walsall - England
Abstract :
Introduction: Multiple myeloma is a rare haematological malignancy of plasma cells commonly presenting in the fifth and sixth
decade. Uncommonly, multiple myeloma can present with cutaneous manifestations. Usually these lesions occur as a result of an
infiltrative extension of osteolytic bone lesions.
Case Presentation: A 72-year-old gentleman with a large malodorous fungating lesion on his right thigh. A skin biopsy demonstrated
that the lesions are deposits of known kappa light chain plasma cell myeloma.
Conclusions: Cutaneous plasmacytoma typically presents as erythematous or violaceous hard and tender nodules or plaques.
Treatment involves chemotherapy, steroids, local radiotherapy and surgery. The discovery of cutaneous metastatic plasmacytomas
can be the first sign of progression of the disease or signal a deteriorating clinical course in multiple myeloma therefore prompt
investigation is essential.
Keywords :
Cutaneous Plasmacytoma , Multiple Myeloma , Skin Disease
Journal title :
Journal of Skin and Stem Cell