Author/Authors :
Gabriele Prado Albuquerque Ferreira, Marilia Universidade Federal do Vale do São Francisco - UNIVASF - Petrolina - PE, Brazil , Abou Ghaouche de Moraes, Fatima Universidade Estadual do Centro-Oeste do Paraná - UNICENTRO Guarapuava - PR, Brazil , Muller do Prado, Leandra Universidade Tecnológica Federal do Paraná - Medianeira - PR, Brazil , Lucia Pascoli, Ana Department of Veterinary Medicine - Regional University of Blumenau (FURB) - Blumenau - SC, Brazil , Vargas Hernandez, Giovanni Universidad Nacional de Colombia - Sede Bogotá, Colombia , de Paula Reis Filho, Nazilton Universidade Estadual Paulista - UNESP - Câmpus Jaboticabal - Jaboticabal - São Paulo, Brazil , Rodrigo Sierra Matiz, Oscar Universidade Estadual Paulista - UNESP - Câmpus Jaboticabal - Jaboticabal - São Paulo, Brazil , Bortolotti Viéra, Rafaela Universidade Estadual Paulista - UNESP - Câmpus Jaboticabal - Jaboticabal - São Paulo, Brazil , Tinucci-Costa, Mirela Universidade Estadual Paulista - UNESP - Câmpus Jaboticabal - Jaboticabal - São Paulo, Brazil , Barboza De Nardi, Andrigo Universidade Estadual Paulista - UNESP - Câmpus Jaboticabal - Jaboticabal - São Paulo, Brazil , Victória Antunes, Anna Universidade Federal do Parará - UFPR - Curitiba - Paraná, Brazil
Abstract :
Introduction: The present report aimed at describing an atypical presentation of a cutaneous transmissible venereal tumor (TVT)
in a dog.
Case Presentation: The case was admitted at the Veterinary Hospital of the Universidade Estadual Paulista (UNESP), Jaboticabal,
São Paulo, Brazil, due to the presence of multiple ulcerated, crusty, and occasionally coalescing cutaneous nodules. The disease
was first diagnosed by a practitioner 15 months before the referral to the UNESP Veterinary Hospital. Thus, the dog had already
been subjected to the vincristine antineoplastic chemotherapy for the treatment of cutaneous TVT 15 months ago. As a diagnostic
approach, cytological, histopathological, and immunohistochemical analyses were performed. The patient was then subjected to
antineoplastic chemotherapy based on vincristine, doxorubicin, and bleomycin protocols; nonetheless, it was not successful, and
the patient passed away 16 months after the primary diagnosis of TVT.
Conclusions: TVT can be more aggressive than usually expected, and the correct diagnosis and appropriate treatment can reduce
the risk of chemotherapy resistance.
Keywords :
Cancer , Chemotherapy , Neoplasm , Treatment
