Title of article :
Cyclodextrins in Skin Formulations and Transdermal Delivery
Author/Authors :
Jicsinszky, Laszlo Department of Drug Science and Technology - University of Turin - Turin - Italy , Cravotto, Giancarlo Department of Drug Science and Technology - University of Turin - Turin - Italy
Abstract :
This mini review aims to describe the main physicochemical properties and characteristics of cyclodextrin derivatives (CDs) having
been used in various skin-related formulations over the last nearly 50 years. Due to many misunderstandings and inconsistent
data on the Internet, the basic properties of CDs, water content, solubility properties, and maximum complexing capabilities are
summarized. CDs are grouped by their solubility properties and briefly described by chemical synthesis to reveal the potential
contaminants. Soluble and insoluble CD-based polymers are also discussed.
Keywords :
Solubility , Synthetic Methods , Structure , Cyclodextrin Polymers , Nanosponges
Journal title :
Journal of Skin and Stem Cell
