Title of article :
Inhibitory Effect of Mentha Piperita Extracts against Herpes Simplex Virus Isolated from Eye Infection
Author/Authors :
Omidian ، Jalil Department of Ophthalmology - Faculty of Medicine - Kermanshah University of Medical Sciences , Sheikhi-Shooshtari ، Fariba Department of Ophthalmology - Faculty of Medicine - Kermanshah University of Medical Sciences , Fazeli ، Maryam WHO Collaborating Center for Reference and Research on Rabies - Pasteur Institute of Iran
Abstract :
Herpes simplex virus (HSV) is one of the common pathogenic viruses of humans bing. This study aimed to determin anti-herpes virus activity of Mentha Piperita extracts in vitro. Mentha Piperita extracts can inhibit HSV infection when the cells treated before viral adsorbtion. HSV-1 were also inhibited by menthol after viral adsorption. HSV-1 viral particles were directly inhibited and viral yield was reduced when treated with Mentha Piperita extracts and menthol. Therefore, Mentha Piperita extracts and menthol showed anti-HSV activities at various stages of the viral replication cycle.
Keywords :
Mentha Piperita , menthol , herpes simplex virus , virus replication , eye infection
Journal title :
Iranian Journal of Virology
Journal title :
Iranian Journal of Virology