Association Of Coronary Artery Disease With Psoriasis In A Group Of Patients In Queen Alia Heart Institute (Qahi) In Jordan

Objective: The aim of our study is to demonstrate the association between psoriasis and CAD in a group of patients at QUEEN ALIA HEART INSTITUTE (QAHI). Methods: This retrospective study was conducted at QUEEN ALIA HEART INSTITUTE from April 2012 to August 2016. 167 psoriatic patients (with moderate to severe psoriasis) and 197 non-psoriatic patients (control group) were matched by sex, age and risk factors of CAD. All patients underwent coronary angiography, and the incidence of coronary artery disease was compared between the two groups. Results: After analysis, the p-value of CAD risk factors in both groups (psoriasis and controls) were: age (41.3 year, 35.4 ,0.04) , male (67% , 64% ,0.06), smoking (60.5% , 56% , 0.4) , HTN (40.5 % , 43% , 0.29 ) ,DM (37.5% ,36.3% ,0.3), hyperlipidemia (20.3% , 17.8% , 0.41), family history (36.1% ,34.4 ,0.05). After matching for all these risk factors, the rate of CAD in psoriasis patients was (8.2%) and (2.1%) in non-psoriatic patients with p-value less than 0.001. Conclusion: Psoriasis (moderate and severe) is an independent risk factor for increasing the risk of coronary artery disease in (sex, age, and other risk factor for CAD) matched patients.