Title of article :
Layered Double Hydroxides (LDHs): An Efficient Catalyst System for the Synthesis of Chiral Aminonitriles
Author/Authors :
Tahoori, Fatemeh Razi Vaccine and Serum Research Institute - Agricultural Research and Extension Organization , Moradinejad, Mona Department of Chemistry - Tehran East branch - Islamic Azad University , Tondfekr, Reza Department of Chemistry - Iran University of Science and Technology , Karbasi, Farnaz Department of Chemistry - Tehran East branch - Islamic Azad University
Abstract :
Strecker reaction is one of the simplest multicomponent reactions. It used for synthesis of chiral α-amino nitriles. This reaction was carried out in the presence of catalytic amount of layered double hydroxides (LDHs). In this study, simple and practical method for the synthesis of this class of catalysts is provided. The results shown that LDH is the good heterogen catalyst for synthesis of chiral α-amino nitriles.
Keywords :
Layered double hydroxide (LDHs) , Strecker reaction , α-Amino acids , Diastereoselectivity
Journal title :
Organic Chemistry Research
