Title of article :
Tertiary cyclic amides in Vilsmeier type reaction with indoles
Author/Authors :
Aghazadeh ، Masomeh Department of Chemistry, Young Researchers and Elite Club - Islamic Azad University, Maku Branch
Abstract :
The reaction of indoles with the complex formed from tertiary cyclic amides and phosphorus oxychloride, followed by basification using sodium hydroxide, was studied. In the case of five member amide rings, 3-(1-alkylpyrrolidine-2-ylidene)3H-indoles were obtained but in the case of six and seven member amide rings, ring opening was occurred and amino ketones were obtained.
Keywords :
3 , (1 , Alkyl , pyrrolidine , 2 , ylidene)3H , indoles , Amino ketones , Indoles , Phosphorus oxy chloride , Vilsmeier reaction
Journal title :
Progress in Chemical and Biochemical Research
Journal title :
Progress in Chemical and Biochemical Research
