Synthesis and Theoretical Studies of [2amino3(ethoxycarbonyl)1,4dihydro1phenyl4pyridinyl] Ferrocene Derivatives

In this study, syntheses of [2amino3(ethoxycarbonyl)1,4dihydro1phenyl4pyridinyl]ferrocene derivatives from reaction of ferrocenecarboxaldehyde, ethyl cyanoacetate, aniline, and acetylenic esters in the presence of piperidine were reported in good yields. The reaction proceeded smoothly and cleanly under mild reaction conditions and no side reactions were observed. The structures of the products were confirmed by IR, 1H NMR, 13C NMR, mass spectroscopy, and elemental analysis. Then, structure, electronic and spectroscopic properties of the synthesized molecules were computed at the CAMB3LYP/jorgeDZP (H,C,N,O) and Def2TZVPPD (Fe) level of theory. First hyperpolarizability value were calculated to describe the nonlinear optical (NLO) properties of these molecules. The HOMOLUMO study to find the band gap of the prepared molecules was extended to calculate global hardness, chemical potential and global electrophilicity for the investigation of the chemical behavior of the compounds. The energies of iron dorbitals and formal electron configurations of iron atom were calculated by natural bond orbital (NBO) analysis.