Author/Authors :
Zahedi, Mohammad Department Of Laboratory Sciences - School Of Allied Medical Science - Student Research Committee - Mazandaran University Of Medical Sciences, Sari, Iran , Abounoori, Mahdi Student Research Committee - Mazandaran University Of Medical Sciences, Sari, Iran , Maddah, Mohammad Moein Student Research Committee - Mazandaran University Of Medical Sciences, Sari, Iran , Mirabi, Ali Student Research Committee - Mazandaran University Of Medical Sciences, Sari, Iran , Sadeghnezhad, Reza Student Research Committee - Faculty Of Health - Health Sciences Research Center - Mazandaran University Of Medical Sciences, Sari, Iran , Rezaei, Ali Akbar Department Of Laboratory Sciences - School Of Allied Medical Science - Student Research Committee - Mazandaran University Of Medical Sciences, Sari, Iran , Goli, Hamid Reza Molecular and Cell Biology Research Center - Faculty Of Medicine - Mazandaran University Of Medical Sciences, Sari, Iran
Abstract :
Introduction: Hospital infections and bacterial antibiotic resistance are numerous issues that have been
reported worldwide over the years and lead to costly and long-term treatment options. The purpose of this
study was to survey the prevalence of nosocomial bacterial infections and antibiotic resistance patterns of
the bacteria in hospitalized patients admitted to a teaching hospital in the north of Iran.
Methods: This cross-sectional study performed by using available data and census methods on all
patients with nosocomial infections (NIs) who were admitted to BO-ALI SINA hospital from March 2017
to March 2018. MS Excel 2016 and SPSS version 16.0 were used for statistical analysis.
Findings: Out of 517 patients with positive bacterial cultures, 57.3% were female. Escherichia coli,
Staphylococcus epidermidis, and Klebsiella pneumonia were the most prevalent agents of NIs. The
highest infection rate in hospital wards was observed in internal medicine, neurology, and intensive care
units, respectively. E. coli showed the highest resistance rate against ampicillin (88.7%) and cephalexin
(74.2%).
Conclusion: Early recognition of the infections with proper infection control procedures can significantly
decrease the incidence of nosocomial infections in hospitals. Various studies have shown that antibiotic
resistance patterns are different in dissimilar regions. Increasing the antibiotic resistance can be a sign of
improper use of antibiotics, indicating the need for more attention to it. Our findings can help physicians
and health care staff to have better treatment options against the bacterial NIs.
Keywords :
Bacteria , Hospital , Antibiotic Resistance , Nosocomial Infection
