Research Paper: The Effects of Two Different Types of Resistance Training Exercise Plus Omega-3-6-9 Supplement on E-selectin and ICAM-1 Adhesion Molecules in Young Overweight Men

Background: Performing regular exercise training and taking inflammation-reducing supplements can be efficient in lowering atherosclerosis risk. The aim of this research was to assess the impact of resistance training (RT) conducted with or without Omega3-6-9 (Omega 3) supplementation in ascending pyramid (AP) or circuit (CR) on plasma levels of E-Selectin and ICAM-1 adhesive molecules in young overweight males. Methods: Sixty healthy overweight men (18-26 years of age) were recruited and randomly allocated to either receive Omega 3 supplement (SU, 2.4 g/d) or placebo (PL, 2% dextrose) for 12 weeks. Topics of SU and PL divided into groups of AP, CR, RT, and Control (C). Levels of plasma E-selectin and ICAM-1 were evaluated and compared before and after the practice training period.ICAM-1 Levels did not change significantly after exercise in any of the groups. Results: E-selectin levels decreased significantly in CR plus SU (P=0.014) and AP plus SU (P=0.012). ICAM-1 did not change significantly in any of the groups. Conclusion: Based on the results of this research, RE plus Omega3-6-9 supplement is efficient in decreasing the amount of E-selectin, but not ICAM-1, regardless of the type of exercise.