Abstract :
Coffee is one of the most
commonly consumed drinks
worldwide. For centuries, medicinal
values and potential toxic effects
related to coffee have been discussed.
Consumption of coffee was not always
welcome by physicians. However, it
has been shown that even physicians
commonly drink coffee as a stimulant
(Giesinger et al., 2015).
Recently, meta-analyses revealed
that drinking coffee induces a dosedependent risk reduction after acute
myocardial infarction (Brown et al.,
2016). In addition, more positive
reports on drinking coffee are being
published including 2016 surprising
announcement by the Agency for
Research on Cancer (IARC) (Brown al., 2016) to discard its own previous report on
cancerogenicity of coffee drinking in humans
(IARC, 1991; Loomis et al., 2016).
If coffee decreases the possibility of
myocardial infarction and it is no longer
harmful from a carcinogenicity point of view, it
is the time to acknowledge Gustav III (1746-
1792 CE) (Encyclopædia Britannica, 2016), the
adventures king of Sweden’s, pioneer
experiment on coffee safety as the first
documented “randomized clinical trial” in
medical history. In the same year that he was
born, the “Misuse and Excesses Tea and Coffee
Drinking Edict” was signed by his father,
Adolph Frederick, and taxes were implemented
on use with heavy fines and confiscation of cups
and dishes for coffee drinkers if they do not
confess they used this psychoactive intoxicant
(Weinberg and Bealer, 2001). Later, a total ban
was implemented in the country
