Title of article :
Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial
Author/Authors :
Engheta, Arman Department of Plastic Surgery - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran , Abianeh, Shahryar Hadadi Department of Plastic Surgery - Razi Hospital - Tehran University of Medical Sciences - Vahdat Eslami st, Tehran , Atri, Ali Department of Plastic Surgery - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran , Sanatkarfar, Mehdi Department of Anesthesiology - Razi Hospital - Tehran University of Medical Sciences, Tehran
Abstract :
We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group. In this double blind randomized controlled trial,
32 patients who continued taking aspirin (intervention group) and 38 patients who stopped taking Aspirin (placebo
group) before surgery were compared in terms of intraoprative and postoperative bleeding problems, hematoma
and local signs of coagulopathy. There was no statistically significant difference in intraoprative bleeding between
the study groups (P = 0.107). We concluded that continuation of Aspirin therapy had no significant effect on bleeding complications in patients who underwent skin tumor surgery.
Keywords :
Acetyl salicylic acid , Skin cancer , Surgery , Bleeding , Complication , Aspirin
Journal title :
Daru:Journal of Pharmaceutical Sciences
