Title of article :
The evaluation of functional results before and after laparoscopic Heller myotomy for achalasia: a single center experience
Author/Authors :
Pooshani, Abdollah Gastroenterology and Liver Diseases Research Center - Research Institute for Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Frootan, Mojgan Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center - Research Institute for Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Abdi, Saeed Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center - Research Institute for Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Jahani-Sherafat, Somayeh Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center - Research Institute for Gastroenterology and Liver Diseases - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Kamani, Freshteh Taleghani hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract :
Aim: The aim of this study was to evaluate and compare the functional results before and after laparoscopic Heller myotomy for
Iranian patients with achalasia.
Background: Achalasia is a severe neuromuscular disorder of the esophagus, characterized by the loss of peristalsis and an inability of
the lower esophageal sphincter (LES) to reach optimal relaxation.
Methods: In this cross sectional study, patients who underwent Heller myotomy for achalasia via laparoscopy in Taleghani Hospital
Tehran, Iran were evaluated. Symptoms including pressure of residual, integrated relaxation sphincter (IRP), pressure of free
drinking, pressure of LES, dysphasia score and peristalsis movement was measured and recorded by manometry before and after (2
months) treating with Heller myotomy.
Results: In this study, 23 patients with achalasia (12 females and 11 males) with a mean age of 30±3.5 years (minimum 20, maximum
44 years) who met the inclusion criteria of the study were examined. Results of this study showed that, all the diagnostic criteria that
were measured before the treatment was significantly different from after the treatment (P<0.05). The average decline in LES, IRP,
Residual Pressure, Free drinking esophagus, and dysphasia score were 23.1 mmHg, 16.24 mmHg, 18,7 mmHg, 18.9 mmHg, and 5.0
unit, respectively. Also the average increase of the peristalsis movement was 8.26±13.7 in 8 patients.
Conclusion: Considering the results of Heller myotomy surgery can be as a treatment of choice for achalasia. Free Drinking pressure
can be a suitable criteria after treatment for evaluation and prediction of the reducing the dysphasia score after the surgery.
Keywords :
Achalasia , Heller myotomy surgery , Free Drinking pressure , dysphasia , Iran
Journal title :
Gastroenterology and Hepatology From Bed to Bench