Title of article :
Study of regulatory promoter polymorphism (-248 G>A) of Bax gene in patients with gastric cancer in the northern provinces of Iran
Author/Authors :
Mirmajidi, Habibeh College of Sciences - Sari Agricultural Sciences and Natural Resources University, Iran , Najafi, Mojtaba Department of Animal Sciences and Fisheries - Sari Agricultural Sciences and Natural Resources University, Iran , Mirmajidi, Tahereh Tehran University of Medical Sciences - Cancer Institute, Tehran, Iran , Nasri Nasrabadi, Nafiseh Student Research Committee - Mazandaran University of Medical Sciences, Sari, Iran
Pages :
9
From page :
36
To page :
44
Abstract :
Aim: The aim of this study is to evaluate the polymorphism in Bax gene and its association with some clinical pathology
traits in gastric cancer.
Background: Gastric cancer is considered as the fourth most common cancer in the north and northwest of Iran. Bcl2
family has a key role in regulation of apoptosis, and any changes in the expression of Bcl2 lead to cancer.
Patients and methods: Blood samples were collected from 100 cases and 89 controls in the northern provinces of Iran
to evaluate promoter polymorphism (-248G
Keywords :
Promoter , Bax gene , Gastric cancer , Polymorphism , PCR-RFLP
Journal title :
Gastroenterology and Hepatology From Bed to Bench
Serial Year :
2016
Record number :
2516382
Link To Document :
