Title of article :
Reference Interval for Fasting Blood Sugar, Triglycerides, Total Cholesterol, Low-Density Lipoprotein, and High-Density Lipoprotein-Cholesterol in Healthy Babolian Individuals
Author/Authors :
Gholami Bahnemiri, Mehdi Department of Biochemistry - School of Medicine - Babol University of Medical Sciences , Amiri, Fereshteh Department of Biology - Islamic Azad University - Science and Research Branch , Khanicheragh, Parisa Department of Clinical Biochemistry - Lorestan University of Medical Sciences , Safizadeh, Fahimeh Iranian Social Security Organization , Mohammadi Tahroodi, Fariba Department of Biochemistry - School of Medicine - Kerman University of Medical Sciences , Akbari Javar, Arefeh Department of Pathobiology - School of Veterinary Medicine - Shahid Bahonar University of Kerman , Aram, Hourieh Department of Immunology - School of Medicine - Shahid Beheshti University of Medical Sciences , Mir, Mostafa Department of Biochemistry - School of Medicine - Babol University of Medical Sciences , Yavari, Negar Department of Physiology - Isfahan University of Medical Science
Abstract :
Background and Aim: Sugar and Lipid disorders are the main risk factors for vascular abnormalities. Due to the gender and age, other variables can influence serum Fasting blood sugar and lipid levels, certifying the determination of population-specific reference interval. This study was designed to investigate the age- and gender-specific reference values for serum Fasting blood sugar (FBS), triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein-cholesterol (HDL) in healthy Babolian adults. Methods: FBS, TC, TG, and HDL were calculating applying the colorimetric method. The Friedewald equation (LDL=TC−HDL−TG/5) was used to calculate LDL concentrations in individuals. After using the exclusion parameters, 519 participants (199 men and 320 women) aged ≥23 years were included. The Clinical Chemistry guidelines of the International Federation applied for characterizing the reference values for samples. Results: Reference values for serum FBS, TG, TC, LDL, HDL were 77.01-107.69 mg/dL, 35.34-204.38 mg/dL, 117.97-242.81 mg/dL, 47.6-137.16 mg/dL and 33.29-67.13 mg/dL in men. In women, reference values for serum FBS, TG, TC, LDL, HDL were 75.03-107.99, 27.49-192.33 mg/dL, 125.84-244.32 mg/dL, 44.08-139.48 mg/dL and 36.66-81.1 mg/dL. FBS, TG, and LDL parameters were higher in men, and TC and HDL parameters were higher in women. Conclusion: Reference values for serum FBS, TC, TG, LDL, HDL in healthy Babolian adults were specified, and these data could supply a clear pathway for better decision making in both clinical settings and prevention.
Keywords :
Cholesterol , Fasting Blood Sugar , Lipid Profile , Reference Interval Values , Triglycerides
