Multiple Myeloma Presenting as Respiratory Stridor

Extramedullary plasmacytoma occurs in 18% of patients with multiple myeloma. Laryngeal involvement in multiple myeloma is rare, and only a few cases have been reported. We present a case of a 44-year-old women with multiple myeloma who presented with stridor due to a mass involving the larynx which was initially proven to be plasmacytoma on biopsy. She had evidence of multiple myeloma of IgA lambda subtype. She was treated with bortezomib containing chemotherapy followed by lenalidomide as maintenance therapy. She attained complete remission and is alive in remission at 3 years of treatment.