Author/Authors :
Abeysundara, Prabath K Postgraduate Institute of Medicine - University of Colombo, Colombo, Sri Lanka , Athukorala, Inoshi Faculty of Medicine - University of Colombo, Colombo, Sri Lanka , Dalpatadu, K.P.C Faculty of Medicine - University of Colombo, Colombo, Sri Lanka , Balendran, Karthiha Postgraduate Institute of Medicine - University of Colombo, Colombo, Sri Lanka , Dilrukshi, M.D.S.A Postgraduate Institute of Medicine - University of Colombo, Colombo, Sri Lanka , Fernando, GMO Postgraduate Institute of Medicine - University of Colombo, Colombo, Sri Lanka
Abstract :
Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis. Thrombotic thrombocytopenic purpura was first described in 1924 by Moschowitz as a disease presenting with a pentad of signs and symptoms (anemia, thrombocytopenia, fever, hemiparesis and hematuria). Previous studies have described atypical manifestations of thrombotic thrombocytopenic purpura such as hemolysis, anemia and thrombosis.
