Author/Authors :
Yousefichaijan, Parsa Department of Pediatric Nephrology - Amirkabir Hospital - Faculty of Medicine - Arak University of Medical Sciences, Arak, Iran , Naziri, Mahdyieh Department of Basic Sciences - Arak University of Medical Sciences, Arak, Iran , Taherahmadi, Hassan Department of Pediatric Nephrology - Amirkabir Hospital - Faculty of Medicine - Arak University of Medical Sciences, Arak, Iran , Kahbazi, Manijeh Department of Pediatric Nephrology - Amirkabir Hospital - Faculty of Medicine - Arak University of Medical Sciences, Arak, Iran , Tabaei, Aram Department of Pediatric Nephrology - Amirkabir Hospital - Faculty of Medicine - Arak University of Medical Sciences, Arak, Iran
Abstract :
Introduction. Urinary tract infection (UTI) is very common in
children. Precocious diagnosis and appropriate treatment are
important because of the permanent disease complications. Zinc
increases the response to treatment in many infections. In this
study, we explored the effect of zinc in treating UTI.
Materials and Methods. Two hundred children with UTI were
divided into 2 groups of 100 who were comparable in terms of age,
sex, urine laboratory profiles, and clinical signs and symptoms.
The control group received a standard treatment protocol for UTI
and the intervention group received oral zinc sulfate syrup plus
routine treatment of UTI.
Results. A faster recovery was observed in the patients receiving
zinc, but abdominal pain was exacerbated by zinc and lasted
longer. Three months after the treatment, there was no significant
difference between the two groups in the time of fever stop and
negative urine culture.
Conclusions. In children with UTI, zinc supplementation has a
positive effect in ameliorating severe dysuria and urinary frequency
while the use of this medication is not recommended in the presence
of abdominal pain.
