Drug Addiction and Vitamin D Supplementation: How to Address a Health Concern in Methadone Treatment?

A research paper written by Ghaderi and colleagues entitled “The effects of vitamin D supplementation on withdrawal symptoms and the expression of inflammatory cytokines and insulin in patients under methadone maintenance treatment: a randomized, double-blind, placebocontrolled trial” has been recently published in your peerreviewed journal (1). In our view, the study is novel and important due to two main reasons: first, authors have highlighted the substantial effects of vitamin D supplementation on reducing the side effects of high doses of methadone administration and promoting the quality of life (QoL) in methadone patients (1).