Author/Authors :
Abdollahi, Soosan Department of Drug and Food Control - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Tofighi, Zahra Department of Pharmacognosy - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Rahimzadeh, Ghazal Department of Food Science and Technology - Science and Research Branch - Islamic Azad University, Tehran, Iran , Babaee, Tahereh Department of Drug and Food Control - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Shamsi, Mohammad Department of Drug and Food Control - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Rezvanifar, Hossein Department of Drug and Food Control - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Saeidi, Elaheh Department of Drug and Food Control - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Mohajeri Amiri, Morteza Department of Drug and Food Control - Faculty of Pharmacy - Tehran University of Medical Sciences, Tehran, Iran , Saffari Ashtiani, Yasaman Department of Drug and Food Control - Faculty of Pharmacy - International Campus, Tehran University of Medical Sciences, Tehran, Iran , Samadi, Nasrin Pharmaceutical Quality Assurance Research Center - The Institute of Pharmaceutical Sciences (TIPS) - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
which were derived from two autochthonous biosurfactant-producing strains, Bacillus amyloliquefaciens NS6 (surfactin), andPseudomonas aeruginosaMN1 (rhamnolipids). Their antioxidant activities were determined by ferric reducing antioxidant power (FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods. Ferric thiocyanate (FTC) assay was used for determination of their lipid peroxidation inhibition capacity. Their effect to reduce the adhesion of Streptococcus mutans on polystyrene surfaces and disruption of its pre-formed biofilms were also investigated. Our results indicated that surfactin showed higher antioxidant activity than rhamnolipids and showed relatively similar efficiency to BHA that suggests it as a good alternative for synthetic antioxidants. In other hand, rhamnolipid conditioned surfaces showed higher antiadhesive and antibiofilm activity in comparison with surfactin treated surfaces.
Keywords :
Biosurfactant , Antioxidant activity , Biofilm , Surfactin , Rhamnolipid
