Author/Authors :
Alizadeh-Navaei, Reza Mazandaran University of Medical Sciences, Sari , Saeedi, Majid Department of Pharmaceutics - Faculty of Pharmacy and Pharmaceutical Sciences Research Center - Mazandaran University of Medical Sciences, Sari , Valadan, Reza Department of Immunology - Mazandaran University of Medical Sciences, Sari , Roozbeh, Fatemeh Mazandaran University of Medical Sciences, Sari , Amjadi, Omolbanin Mazandaran University of Medical Sciences, Sari , Zaboli, Ehsan Mazandaran University of Medical Sciences, Sari , Moosazadeh, Mahmood Mazandaran University of Medical Sciences, Sari , Ranjbaran, Hossein Mazandaran University of Medical Sciences, Sari , Qazizadeh, Zinab Mazandaran University of Medical Sciences, Sari , Akbari-Malekshah, Ali Mazandaran University of Medical Sciences, Sari , Assadi, Touraj Department of Emergency Medicine - Faculty of Medicine - Mazandaran University of Medical Sciences, Sari , Omrani-Nava, Versa Mazandaran University of Medical Sciences, Sari , Hedayatizadeh-Omran, Akbar Mazandaran University of Medical Sciences, Sari
Abstract :
Background: Coronavirus is a single-stranded RNA virus, causing an epidemic of pneumonia and acute respiratory distress syndrome
(ARDS) worldwide in late 2019.
Objectives: In addition to the clinical symptoms, laboratory diagnosis can greatly help diagnose the diseases; therefore, this study
aimed to analyze laboratory parameters in patients with COVID-19.
Methods: In this cross-sectional study, the laboratory data of 2563 patients with COVID-19 admitted to hospitals affiliated with
Mazandaran University of Medical Sciences were extracted from hospital information systems (HIS). The data were recorded on
Excel and analyzed through t-test, chi-squared, and Fisher’s exact tests in SPSS 19 at the significance level of P < 0.05.
Results: Out of 2563 patients with a mean age of 55.1 16.7 years, 1409 (55%) were male, and 1154 (45%) were female with a mean
age of 55.7 16.8, and 54.3 16.6 years, respectively. As the most frequent clinical findings, ESR, CRP, and LDH were increased by
83.5%, 71%, and 69.3% of the patients, respectively. Other research findings included lymphopenia, disturbed INR, abnormal SGOT,
abnormal alkaline phosphatase (ALP), and increased lactate dehydrogenase (LDH), which were significantly higher in men than in
women and was different between age groups.
Conclusions: Conducting simple, convenient, and inexpensive laboratory tests can be helpful in the diagnosis of COVID-19.
Keywords :
Coronavirus , COVID-19 , ARDS , Laboratory Test
