Comments on “Cardiovascular Complications in Obstructive Sleep Apnea Syndrome”

I have read the review article entitled “Cardiovascular Complications in Obstructive Sleep Apnea Syndrome”. I would like to make some contributions to this successful article and congratulate its authors. In the review article, the authors mentioned the effect of OSA on cardiovascular system that can create both long term and acute changes in cardiovascular function like hypertension, arrhythmia, myocardial infarction, pulmonary hypertension and congestive heart failure. Firstly, sleep apnea is a very common clinical problem and the most common type of sleep apnea is OSA. There are clinical factors leading to OSA like genetic factors, smoking, obesity, upper airway anatomic abnormalities, endocrine disturbances and drugs. Severity of OSA which can be calculated as the AHI in PSG analysis based on AASM. Secondary, cardiovascular disease is one of the most important causes of mortality in the (1). A more developed use of evidence-based medical therapies, along with modifications in people’s life style and alterations in risk factors at a population level have resulted in a decrease in heart disease mortality rates in the United States (2, 3). The mechanisms involved in the cardiovascular consequences of OSA have been widely reviewed (4) OSA is associated with increased mortality and mostly increases mortality cardiovascular disease.