Author/Authors :
Fazel, Mojtaba Department of Pediatrics, Valiasr Hospital - Imam Khomeini Medical Complex - Tehran University of Medical Science, Tehran, Iran , Nili, Fatemeh Department of Pathology - Imam Khomeini Hospital Complex - Tehran university of Medical Sciences, Tehran, Iran , Raeeskarami, Reza Department of Pediatrics, Valiasr Hospital - Imam Khomeini Medical Complex - Tehran University of Medical Science, Tehran, Iran , Akhlaghi, Maassoumeh Rheumatology Research Center - Tehran University of Medical Sciences, Tehran, Iran , Faraji-Goodarzi, Mojgan Department of Pediatrics - Lorestan University of Medical Sciences, Khorramabad, Iran , Moghtaderi, Mastaneh Department of Pediatric Nephrology - Chronic Kidney Disease Research Center - Tehran University of Medical Sciences, Tehran, Iran , Akbari Asbagh, Parvin Department of Pediatric Nephrology - Chronic Kidney Disease Research Center - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
Systemic lupus erythematosus is an autoimmune disease associated with systemic involvement. Various organs including skin, kidneys, joints, heart, and central nervous system, may be affected. One of the serious organ damages in SLE is renal involvement as lupus nephritis, which occurs in 50-75% of children with SLE. Approximately 6-12% of pediatric SLE may develop other conditions, such as JIA, JDM, and polymyositis, scleroderma, and Crohn's disease. Henoch schönlein purpura (HSP) is another disease that accompanies with SLE. There have been several reports of HSP as the primary manifestation of SLE. In this report, we aim to highlight lupus nephritis as the first presentation of SLE and its association with HSP in our patient, a 6-year-old boy with lupus nephritis and past history of HSP 4 years before initiating of SLE.
