Author/Authors :
Çiloğlu, Emine Department of Ophthalmology - Adana City Training and Research Hospital, Adana, Turkey , Unal, Fikret Department of Ophthalmology - Adana City Training and Research Hospital, Adana, Turkey , Alyamac Sukgen, Emine Department of Ophthalmology - Adana City Training and Research Hospital, Adana, Turkey , Kocluk, Yusuf Department of Ophthalmology - Adana City Training and Research Hospital, Adana, Turkey , Cetin Dogan, Nese Department of Ophthalmology - Adana City Training and Research Hospital, Adana, Turkey
Abstract :
Purpose: To evaluate the macular microvasculature in smokers in comparison to healthy subjects using optical coherence tomography
angiography (OCTA).
Methods: Fifty chronic, regular smokers and 50 healthy non‑smokers, as a control group, were recruited for the study. Foveal avascular
zone (FAZ) area (mm2) and vessel density (VD) (%) in the superficial (SCP) and deep capillary plexus (DCP) were evaluated.
Results: FAZ area was 0.424 ± 0.100 mm2 in the smoker group and 0.333 ± 0.093 mm2 in the non‑smoking control group (P = 0.002).
The deep foveal VD was 31.76 ± 6.33% in the smoker group and 53.09 ± 5.88% in the non‑smoking control group (P = 0.006).
Superficial foveal and parafoveal, deep parafoveal VD were not statistically different between the groups (P = 0.120), (P = 0.337), (P
= 0.287), respectively.
Conclusion: In our study, there was an enlargement of FAZ and reduction of foveal VD at DCP in the eyes of smokers compared with
non‑smoking adults.
Keywords :
Capillary plexus , Foveal avascular zone , Optical coherence tomography angiography , Smoking , Vessel density