Author/Authors :
Asadi, Zahra Department of Nutrition - Faculty of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Moghbeli, Meysam Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Khayyatzadeh, Saeid Metabolic Syndrome Research Center - Mashhad University of Medical Sciences, Mashhad, Iran , Mohammadi Bajgiran, Maryam Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Ghaffarian Zirak, Roshanak Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Zare-Feyzabadi, Reza Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Eidi, Marziyeh Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Taheri bonakdar, Mahdi Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Davari, Hafeze Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Mahmoudi, Ali Asghar Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Sheikh Andalibi, Nazanin Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Ferns, Gordon A Nutrition and Food Security Research Centre - Shahid Sadoughi University of Medical Sciences, Yazd, Iran , Ghazizadeh, Hamideh Student Research Committee - Mashhad University of Medical Sciences, Mashhad, Iran , Ghayour-Mobarhan, Majid Department of Medical Genetics and Molecular Medicine - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
Background: The association between the presence of dyslipidemia and major dietary patterns
was examined in an adult Iranian population.
Study design: A cross-sectional study.
Methods: This cross-sectional study was conducted among 4672 adults aged 35-65 yr old based
on data from the Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) Study initiated in
2010. Anthropometric and blood laboratory measurements were collected for all participants.
Dietary intake was assessed using a validated 65-item food frequency questionnaire (FFQ). Dietary
patterns were identified using factor analysis.
Results: The overall prevalence of dyslipidemia was 88% including elevated total cholesterol
(38.9%), triglyceride (35.2%), low-density lipoprotein cholesterol (LDL-C) (35.3) or decreased level
of high-density lipoprotein cholesterol (HDL-C) (68.9%). After adjusting for potential confounding
factors, participants with higher scores for a Western pattern with lower physical activity level and
educational attainment, and higher current smoking habit, increased the risk of having a raised
LDL-C (OR=1.17; 95% CI: 1.02, 1.34; P=0.02). However, there was no significant association
between adherence to this dietary pattern and other types of dyslipidemia. There was no significant
association between a balanced dietary pattern and dyslipidemia and its components (OR=0.90;
95% CI: 0.68, 1.18; P=0.431).
Conclusion: Dyslipidemia was more prevalent among individuals with higher consumption of a
western dietary pattern. A direct association was found between adherence to Western dietary
pattern and LDL-C level.
