Author/Authors :
Ahrabi, Behnaz Laser Application in Medical Sciences Research Center - Shahid Beheshti University of Medical Sciences, Tehran , Bahrami, Maryam Department of Biology and Anatomical Sciences - school of medicine - Shahid Beheshti University of Medical Sciences, Tehran , Moghadasali, Reza Department of Stem Cells and Developmental Biology - Cell Science Research Center - Royan Institute for Stem Cell Biology and Technology - ACECR, Tehran , Zamanian-Azodi, Mona Proteomics Research Center - Shahid Beheshti University of Medical Sciences, Tehran , Khoramgah, Maryam Sadat Laser Application in Medical Sciences Research Center - Shahid Beheshti University of Medical Sciences, Tehran , Tabatabaei Mirakabad, Fatemeh Sadat Laser Application in Medical Sciences Research Center - Shahid Beheshti University of Medical Sciences, Tehran , Darabi, Shahram Cellular and Molecular Research Center - Qazvin University of Medical Science , Abbaszadeh, Hojjat Allah Laser Application in Medical Sciences Research Center - Shahid Beheshti University of Medical Sciences, Tehran
Abstract :
Objective: The purpose of this study is to investigate the effects of low-power lasers on kidney disease by investigating several studies.
Methods: A number of articles from 1998 to 2019 were chosen from the sources of PubMed,
Scopus, and only the articles studying the effect of low-power lasers on kidney disease were
investigated.
Results: After reviewing the literature, 21 articles examining only the effects of low-power lasers
on kidney disease were found. The results of these studies showed that the parameter of the lowpower laser would result in different outcomes. So, a low-power laser with various parameters
can be effective in the treatment of kidney diseases such as acute kidney disease, diabetes,
glomerulonephritis, nephrectomy, metabolic syndrome, and kidney fibrosis. Most studies have
shown that low-power lasers can affect TGFβ1 signaling which is the most important signaling in
the treatment of renal fibrosis.
Conclusion: Lasers can be effective in reducing or enhancing inflammatory responses, reducing
fibrosis factors, and decreasing reactive oxygen species (ROS) levels in kidney disease and glomerular cell proliferation.