Title of article :
Iodine-Promoted Oxidative Cyclization for Green Synthesis of 2-Arylquinazolin- 4(3H)-Ones in Polyethylene Glycol (PEG)
Author/Authors :
Soheilizad, Mehdi CinnaGen Medical Biotechnology Research Center - Alborz University of Medical Sciences , Mahdavib, Mohammad Endocrinology and Metabolism Research Center - Endocrinology and Metabolism Clinical Sciences Institute - Tehran University of Medical Sciences
Abstract :
A metal-free and iodine promoted oxidative system for cyclization of primary
benzyl amines with anthranilamide to afford 2-arylquinazolin-4(3H)-ones in
PEG-400 as a green, inexpensive, non-toxic and reusable solvent medium has
been developed.
Keywords :
Anthranilamide , Benzyl amine , Iodine-promoted , Polyethylene glycol (PEG) , Quinazoline-4(3H)-ones
Journal title :
Frontiers in Chemical Research
