Author/Authors :
Abdolkarimi, Babak Department of Pediatric Hematology and Oncology - Lorestan University of Medical Sciences, Khoramabad, Iran , Alghasi, Aarash Department of Pediatric Hematology and Oncology - Ahvaz University of Medical Science, Ahvaz, Iran , Moeini, Mona Mahak Pediatric Cancer Center, Tehran, Iran , Hashemieh, Mozhgan Department of Pediatric Hematology and Oncology - Shahid Beheshti University of Medical Science, Tehran, Iran , Forutani, Shahab General Physician - Lorestan University of Medical Sciences, Khoramabad, Iran
Abstract :
Neuroblastoma is an extracranial solid tumor that is most commonly observed in
children, yet it is rare to have brain metastasis in neuroblastoma during primary
involvement or relapse. In this article, we report a successful treatment of high risk
neuroblastoma with primary leptomeningeal metastasis based on developing countries
facilities and explain combination chemotherapy (a classic regimen with salvage
regimen based on temozolamid and methotroxate intratechal chemotherapy and
localized radiation therapy) as a multimodal therapy.
