Author/Authors :
Mohammadzadeh, Elham Biochemistry of Nutrition Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Arabpour Dahoue, Mahla Metabolic Syndrome Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Sahebkar, Amirhosein Department of Medical Biotechnology - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Kianoush, Tayebeh Biochemistry of Nutrition Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Avan, Amir Metabolic Syndrome Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Nezafati, Pouya Cardiac Rehabilitation Research Center - Cardiovascular Research Institute - Isfahan University of Medical Sciences, Isfahan, Iran , Sadabadi, Fatemeh Department of Medical Biotechnology - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Ghazizadeh, Hamideh Metabolic Syndrome Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Safar Soflaei, Sara Metabolic Syndrome Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Mohammadzadeh, Mahsa Biochemistry of Nutrition Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Nasrfard, Samira Biochemistry of Nutrition Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Safarian, Mohammad Biochemistry of Nutrition Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Norouzy, Abdolreza Metabolic Syndrome Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Parizadeh, Mohammad Reza Biochemistry of Nutrition Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran , Ghayour-Mobarhan, Majid Biochemistry of Nutrition Research Center - School of Medicine - Mashhad University of Medical Sciences, Mashhad, Iran
Abstract :
Background: Although dietary management is the principle intervention for treating
obesity, noninvasive body-contouring methods are also gaining currency.
We aimed to explore the effects of combined radiofrequency (RF) and ultrasound (US)
body contouring on anthropometric indices, hematological markers, and anti-HSP27
levels in overweight females.
Methods: In this randomized control clinical trial, fifty overweight females were
enrolled and divided into two groups. Each participant was prescribed a diet with a daily
calorie deficit of 500 kcal. RF and US were each used once a week for 5 weeks in the
intervention group. Anthropometric and hematological markers were measured in all
subjects before and after the intervention.
Results: Abdominal circumference (AC), waist circumference (WC), body mass index,
and body fat mass were reduced significantly in both groups (p < 0.001). However, the
mean reduction in AC (p < 0.05) and WC (p < 0.001) were significantly greater in the
intervention group compared with the control group. Moreover, levels of WBC, HCT,
Hb, MCV, and MCH were significantly reduced after the RF-US intervention, although
all the changes were in the normal range, suggesting that this therapy did not have
adverse effects on hematological parameters. Also, the level of anti-HSP27 did not show
any significant change.
Conclusion: Our study suggests that body-contouring devices based on RF and US
cavitation reduce measures of adiposity and do not have adverse effects on
hematological factors, liver function markers, and HSP27 level in overweight women.
Further investigations are required to explore the value of this method in a larger
multicenter setting.
