Author/Authors :
Paciuc-Beja, Migue Ophthalmology Department - Centro Medico ABC, Av Carlos Fernandez Graef, Mexico City, Mexico , Meizner-Grezemkovsky, Daniela Retina Department - Asociacion para Evitar la Ceguera en Mexico, Vicente Garcia Torres, Mexico City, Mexico , Paciuc, Mario Department of Statistics - Rice University, Houston TX, USA , Sanchez-Santos, Idaira Retina Department - Asociacion para Evitar la Ceguera en Mexico, Vicente Garcia Torres, Mexico City, Mexico , Ruiz-Roman, Anabeli Retina Department - Asociacion para Evitar la Ceguera en Mexico, Vicente Garcia Torres, Mexico City, Mexico , Fack, Ashlee Retina Department - Asociacion para Evitar la Ceguera en Mexico, Vicente Garcia Torres, Mexico City, Mexico , Lisker-Cervantes, Andres Retina Department - Asociacion para Evitar la Ceguera en Mexico, Vicente Garcia Torres, Mexico City, Mexico , Mendieta, Gerardo Ophthalmology Department - Centro Medico ABC, Av Carlos Fernandez Graef, Mexico City, Mexico , Morales-Canton, Virgilio Retina Department - Asociacion para Evitar la Ceguera en Mexico, Vicente Garcia Torres, Mexico City, Mexico , Quiroz-Mercado, Hugo Retina Department - Asociacion para Evitar la Ceguera en Mexico, Vicente Garcia Torres, Mexico City, Mexico
Abstract :
Oculocardiac reflex (OCR) has been described to occur with mechanical manipulation of the eye, eyelids or orbit. There are no reports in the literature of OCR during intravitreal injection (IVI). This may be due to the fact that heart rate is not monitored during the procedure. We aimed to evaluate OCR during IVI. A total of 532 patients were enrolled in the study at Asociacion para Evitar la Ceguera en Mexico. Mexico City, Mexico. IVI was performed on one eye in every patient with diabetic retinopathy (DR), age related macular degeneration (AMD) or choroidal neovascularization (CNV) secondary to pathological myopia. Heart rate was monitored with a pulse oximeter before, during and after injection. OCR was defined as a 20% decrease or more of basal heart rate. The population enrolled included 270 females and 262 males with mean age of 63.8 years. A decrease in heart rate of 20% or more occurred in 18 patients during IVI (3.3%; 95% confidence interval 1.85% and 4.92%). OCR was asymptomatic in these patients. OCR occurred in 3.3% of our patients during IVI. Hence, OCR must be considered when performing IVI.
