Title of article :
Synthesis of oxazole derivatives using N-formylmorpholine as green solvent: study of antimicrobial activity
Author/Authors :
Firoozi Khanghah, Parvaneh National Petrochemical Company (NPC) - petrochemical Research and Technology Company, Arak Center, Iran , Souri, Sanaz National Petrochemical Company (NPC) - petrochemical Research and Technology Company, Arak Center, Iran
Abstract :
Abstract: An efficient synthesis of oxazoles in water is described via reaction between arylisocyanate, and alkyl bromides in the presence of N-formylmorpholine. The antimicrobial activity of some synthesized compounds was studied employing the disk diffusion test on Gram-positive bacteria and Gram-negative bacteria. The results of disk diffusion test showed that these compounds prevented the bacterial growth.
Keywords :
Dialkyl acetylenedicarboxylates. , Trialkyl phosphite , 2H-pyran
Journal title :
Iranian Journal of Organic Chemistry
