Evaluation of Antibiotic Prophylaxis Administration at the General and Neuro-Surgery Ward of a Teaching Hospital in Tehran, Iran

The common cause of healthcare-associated infections is surgical site infections (SSIs). The appropriate use of antibiotic prophylaxis plays an important role in the prevention and reduction of surgical site infection. So, this study was evaluated the antibiotics prophylaxis administration in surgical patients. A prospective cross-sectional study was conducted on surgical patients from July 2015 to December 2016. Data were collected for all patients who undergoing surgery and met inclusion criteria. CDC Guideline for wound classification and antibiotic prophylaxis administration were used. SPSS software version 21 was used for data analysis of descriptive statistics. A total of 134 patients who undergoing surgery and met the study criteria were evaluated. Of these, 81 (60.4%) were males. The mean+SD age of the participants was 40.74+18.3. Most commonly used agent was vancomycin plus ceftazidime (71.6%). Duration of antibiotic administration and appropriate antibiotics were not compatible with guidelines. Educational interventions are necessary to improve administration of antibiotic prophylaxis prior to surgery and reduce surgical site infection.