Title of article :
Two Iridoid Structures from Eremostachys macrophylla Montbr. & Auch. Rhizomes
Author/Authors :
Delazar, Abbas Drug Applied Research Center and Faculty of Pharmacy - Tabriz University of Medical Sciences, Tabriz, Iran , Asnaashari, Solmaz Biotechnology Research Center - Tabriz University of Medical Sciences, Tabriz, Iran
Abstract :
The air- dried and ground rhizomes of Eremostachys macrophylla Montbr.
& Auch., as wild-growing plant in East Azerbaijan province, of Iran, were
extracted with n-hexane, dichloromethane (DCM) and methanol (MeOH)
solvents using a soxhlet apparatus. The 10% MeOH in water Sep-Pak
fractions of the MeOH extract was subjected to preparative reversedphase
high performance liquid chromatography (RP-HPLC) and the
isolated pure compounds were identified by one- dimensional nuclear
magnetic resonance (1D-NMR) spectroscopic technique. The obtained
results showed the presence of two pure components, 6- Hydroxyl
Loganin, (1) and Lamalbide (2) with iridoid structures. The results
demonstrated the rhizomes of E. macrophylla could be a good source of
iridoids.
Keywords :
Iridoid , Lamalbide , 6- Hydroxyl Loganin , Eremostachys Macrophylla
Journal title :
Journal of Reports in Pharmaceutical Sciences