Immune Dysregulation in Diseases

oday, only a few diseases have remained that their pathology is not somehow affected by dysregulation in immune responses. Extensive literature review reveals that footprints of dysregulation in the immune response are seen in nearly all diseases, including autoimmune diseases, allergies, infections, cancers, even pulmonary, cardiovascular, dermal, ocular, otorhinolaryngological, and gynecological diseases as well as psychological disorders. It is not always easy, except in congenital or primary immunodeficiency disorders, to judge the primary or secondary nature of this dysregulation; however, what is certain is that resolving or reversing this immune response dysregulation helps a lot in treating the disease and patient’s recovery. Therefore, identifying different mechanisms in immune responses in health or, in other words, recognizing different patterns of immune dysregulation can help in protecting individual’s health and preventing the disease as well as improving pathological conditions by resetting these responses and restoring balance in the immune system