Author/Authors :
Halbony, Hala Faculty of Medicine - University of Jordan, Amman, Jordan , Salman, Khadija General Surgery Department - University of Jordan, Amman, Jordan , Alqassieh, Ahmad General Surgery Department - University of Jordan, Amman, Jordan , Albrezat, Mutaz General Surgery Department - University of Jordan, Amman, Jordan , Hamdan, Ahmad Istanbul Medeniyet University - Goztepe Research and Training Hospital - General Surgery Department, Istanbul, Turkey , Abualhaija’a, Ali Istanbul Medeniyet University - Goztepe Research and Training Hospital - General Surgery Department, Istanbul, Turkey , Alsaeidi, Omar Istanbul Medeniyet University - Goztepe Research and Training Hospital - General Surgery Department, Istanbul, Turkey , Masad Melhem, Jamal General Surgery Department - University of Jordan, Amman, Jordan , Sagiroglu, julide Istanbul Medeniyet University - Goztepe Research and Training Hospital - General Surgery Department, Istanbul, Turkey , Alimoglu, Orhan Istanbul Medeniyet University - Goztepe Research and Training Hospital - General Surgery Department, Istanbul, Turkey
Abstract :
Background: Multiple risk factors contribute to the development of breast cancer, including age, positive family history, early
menarche, late menopause and the strongest factor being female gender. In this study, we aimed to investigate the proportion of breast
cancer patients with certain risk factors, the prevalence of each cancer type, in addition to the surgical procedures performed.
Methods: The medical records of patients diagnosed with breast cancer from January 2010 to November 2015 were evaluated
retrospectively regarding demographics, breast cancer risk factors, comorbidities, diagnostic methods, tumor location, cancer type and
stage, pathological findings, tumor markers, harvested lymph nodes and the types of surgical procedures. The collected data were
statistically analyzed as number, mean, and frequency as percentages. Cases with deficient medical records were excluded from the
analysis of certain parameters.
Results: The sample consisted of 120 patients, 118 (98.3%) of whom were women. The mean age was 56.5±12.0 years. The most
common diagnostic method at presentation was self-exam in 93.3% of patients. Invasive ductal carcinoma was the most common type
of tumor (80.0%). The pathological stages could be determined for only 106 patients, and 26 patients (24.5%) were at stage 1 disease,
45 patients (42.5%) were at stage 2 whereas 34 patients (32.1%) were at stage 3. According to the results of pathological examinations,
72.6% (85 patients) of the cases were estrogen receptor positive, 61.2% (71 patients) were progesterone receptor positive while 24.8%
(27 patients) were HER positive. Modified radical mastectomy (MRM) was performed in 52 (43.3%) patients and wide local excision
(WLE) was preferred in 46 (38.3%) cases.
Conclusion: Advanced age, positive family history, and prolonged estrogen exposure were remarkable in the majority of patients.
Moreover, the most common type of breast cancer was invasive ductal carcinoma, and around half of the patients presented at stage 2
disease. Modified radical mastectomy and WLE were the most commonly performed surgical procedures.
