Author/Authors :
Shirazi, Mehdi Department of Urology - Shiraz University of Medical Science, Shiraz, Iran , Aminsharifi, Alireza Department of Urology - Shiraz University of Medical Science, Shiraz, Iran , Ahmed, Faisal Department of Urology - Shiraz University of Medical Science, Shiraz, Iran , Makarem, Alireza Department of Urology - Shiraz University of Medical Science, Shiraz, Iran , Zahraei, Alihossein Student Research Committee - Shiraz University of Medical Science, Shiraz, Iran , Asmaarian, Naeimehossadat Department of Biostatics - Shiraz University of Medical Science, Shiraz, Iran
Abstract :
Background: To evaluate the outcome of retrograde endopyelotomy as a minimally invasive option for management of failed open
pyeloplasty in children and assess how the duration of post-procedural stenting may affect the endopyelotomy outcome.
Methods: A total of 15 patients with secondary UPJO (Ureteropelvic junction obstruction) underwent retrograde endopyelotomy.
The procedure was done using low-energy monopolar electrocautery hook under direct vision of pediatric ureteroscope and control of
fluoroscopy. Double J stent was placed after the operation in all cases. Stent was removed in another session, 8 weeks (Group A, n=7)
vs. 12 weeks (Group B, n=8) after endopyelotomy. Patients in both Groups were followed one, six and twelve months after the stent
removal, and the anteroposterior renal pelvis diameter (APD), renal cortical thickness (CT) and degree of hydronephrosis (HDN) were
recorded using the repeated measure test. P-value less than 0.05 were significant. We analyzed the data using SPSS software, version
20.
Results: The median interquartile range (IQR) age at time of surgery for group A and B were 24 (62) months and 12 (50) months
respectively. Median (IQR) times between previous pyeloplasty and endopyelotomy were 6 (6) months and 12 (8.5) months in groups
A and B, respectively. The success rate of endopyelotomy after 12 months was 57.1% in group A and 87.5% in group B. The
resolution of HDN was more prominent in the 12 week stenting group compared to the 8 week group during the 12 months follow-up
period (p=0.030). The APD and CT in group B compared to group A was improved during follow-up period.
Conclusion: A higher one-year success rate of retrograde endopyelotomy in terms of improvements in the degree of HDN, APD and
CT was observed when the double j stent was remained for 12-weeks rather than 8-weeks. This observation need to be validated in a
large cohort study with a long term post procedural follow up.
Keywords :
Double-J stent , Endopyelotomy , Treatment failure , Pyeloplasty , Ureteropelvic junction obstruction
