Synthesis, characterization and application of Fe3O4@ MCM-BP as a Novel Nanomagnetic Reusable Basic Catalyst for the one Pot Solvent- Free Synthesis of Dihydropyridine, Polyhydroquinoline and Polyhydroacridine Derivatives via Hantzsch Multicomponent Condensation Reaction

By the immobilization of bipyridinium chloride onto mesoporous MCM-41encapsulated Fe3O4 nanoparticles via a simple post-synthesis method, a totally new organic–inorganic hybrid nanocomposite was formulated. The heterogeneous hybrid nanomagnetic composite was characterized by Fourier Transform InfraRed (FT-IR), X-Ray powder Dffraction (XRD), Scanning Electron Microscope (SEM), Transmission Electron Microscope (TEM), Vibrating Sample Magnetometer (VSM) and Thermal Gravimetric Analytical (TGA). The potential applications of this novel nanomagnetic and recyclable basic nanocomposite, Fe3O4@MCM-BP, were also investigated for solvent- free synthesis of 1,4-dihydropyridine, polyhydroquinoline and polyhydroacridine derivatives via Hantzsch multicomponent condensation reaction. High isolated yields, operational simplicity, clean reaction conditions and minimum pollution of the environment, makes the procedure a useful and appealing process in organic transformation.