Author/Authors :
Mohammadi, Mohammad Kerman Oral and Dental Diseases Research Center , Mohammadi, Mohammad kerman university of medical sciences - Dental School - Department of Periodontics, كرمان, ايران , Mofid, Rasool shahid beheshti university of medical sciences - Dental School - Department of Periodontics, تهران, ايران , Shokrgozar, Mohammad Ali Pasteur Iinstitute of Iran - National Cell Bank of Iran, تهران, ايران
Abstract :
Tissue-engineered gingival graft was used for regenerating facial gingiva around an implant at lower left first premolar area with insufficient attached gingiva. Engineered gingival graft was produced by mixing 250 ml bovine skin collagen with 250 ml nutritional medium containing human gingival fibroblasts (2×10^5). 3 months post-surgery, there were gains in the attached gingiva compared to pre-surgery. The histological examination revealed a keratinized tissue on the treated site. Based on the result of this investigation, this graft was safe and capable of generating keratinized gingiva.
Keywords :
Tissue engineering , Gingiva , Peri , implant soft tissue , Attached gingiva , Keratinized gingiva